{"product_id":"semax-5mg","title":"SEMAX 5mg","description":"\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBatch HPLC tested at 98.5%+ purity\u003c\/li\u003e\n\u003cli\u003eStore frozen long term or in fridge when ready to be used\u003c\/li\u003e\n\u003cli\u003eSold for research purposes only\u003c\/li\u003e\n\u003cli\u003eContact us for Wholesale Orders\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e \u003cspan\u003e \u003ca href=\"https:\/\/zenovussciences.com\/certificate-of-analysis-finder\" rel=\"noopener\" target=\"_blank\"\u003e \u003cb\u003eSearch our database for full COA analytics here.\u003c\/b\u003e \u003c\/a\u003e \u003c\/span\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eSemax\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms \/ Designations: \u003c\/strong\u003eSemax, ACTH(4–7) Pro-Gly-Pro, Met-Glu-His-Phe-Pro-Gly-Pro\u003cbr\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 80714-61-0\u003cbr\u003e\u003cstrong\u003eMolecular Formula: \u003c\/strong\u003eC37H51N9O10S\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~813.92 g\/mol\u003cbr\u003e\u003cstrong\u003ePeptide Length:\u003c\/strong\u003e 7 amino acids\u003cbr\u003e\u003cstrong\u003ePeptide Type:\u003c\/strong\u003e Synthetic neuropeptide (ACTH(4–7) analogue)\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99 % (HPLC, typical)\u003cbr\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e White to off-white lyophilised powder\u003cbr\u003e\u003cstrong\u003ePack Size:\u003c\/strong\u003e 5 mg (typical)\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Desiccated, protected from light, stored at –20 °C or below\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in water and buffered aqueous solutions\u003c\/p\u003e\n\u003ch3\u003eDescription \u0026amp; Mechanism\u003c\/h3\u003e\n\u003cp\u003eSemax is a synthetic heptapeptide derived from the adrenocorticotropic hormone fragment ACTH(4–7), modified with a C-terminal Pro–Gly–Pro sequence to enhance metabolic stability. It was developed for experimental investigation of neuropeptide signalling, neuromodulation, and central nervous system regulatory pathways.\u003c\/p\u003e\n\u003cp\u003eIn biochemical and cellular research systems, Semax has been studied for its interactions with neuronal signalling pathways associated with neurotrophic factors, synaptic plasticity, and stress-response regulation. Experimental models commonly investigate its effects on intracellular signalling cascades, gene expression related to neurotrophins, and modulation of neurotransmitter systems. Observed molecular responses are dependent on experimental design, concentration, and model system.\u003c\/p\u003e\n\u003ch3\u003eApplications in Research\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAs a molecular probe for studying neuropeptide-mediated signalling pathways.\u003c\/li\u003e\n\u003cli\u003eInvestigation of neuronal plasticity, neurotrophic signalling, and stress-related molecular mechanisms.\u003c\/li\u003e\n\u003cli\u003eIn vitro and in vivo research examining peptide stability and CNS-active peptide analogues.\u003c\/li\u003e\n\u003cli\u003eUse as a reference compound in neurobiology and peptide signalling research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSpecifications Summary\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePurity (\u003c\/strong\u003eHPLC): ≥ 99 %\u003cbr\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e White to off-white lyophilised powder\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~813.92 g\/mol\u003cbr\u003e\u003cstrong\u003ePeptide Type:\u003c\/strong\u003e Synthetic ACTH-derived neuropeptide\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Water, buffered aqueous solutions\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e –20 °C, desiccated, protected from light\u003cbr\u003e\u003cstrong\u003ePack Size:\u003c\/strong\u003e 5 mg\u003c\/p\u003e\n\u003ch3\u003eHandling, Reconstitution \u0026amp; Stability\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eWeigh under dry conditions; peptide is hygroscopic.\u003c\/li\u003e\n\u003cli\u003eReconstitute in sterile water or appropriate buffered aqueous solution.\u003c\/li\u003e\n\u003cli\u003eAvoid vigorous agitation during dissolution.\u003c\/li\u003e\n\u003cli\u003eFilter sterilize if required (e.g. 0.22 µm) prior to use.\u003c\/li\u003e\n\u003cli\u003eAliquot and store reconstituted solutions at –20 °C or lower.\u003c\/li\u003e\n\u003cli\u003eAvoid repeated freeze–thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePrecautions \u0026amp; Notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eExperimental behaviour of Semax is influenced by neuronal model, receptor expression, peptide concentration, and exposure duration.\u003c\/li\u003e\n\u003cli\u003eBuffer composition, pH, and ionic strength may affect peptide stability.\u003c\/li\u003e\n\u003cli\u003eAppropriate controls are recommended to distinguish specific from non-specific effects.\u003c\/li\u003e\n\u003cli\u003eIntended strictly for laboratory research use; not for human or veterinary application.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eAshmarin I.P. et al. Semax as a regulator of neurotrophic factors. Neuroscience and Behavioral Physiology, 1997.\u003cbr\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9404683\/\" rel=\"noopener\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/9404683\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eGusev E.I. et al. Neuropeptide Semax in experimental models of brain function. Neuroscience and Behavioral Physiology, 2000.\u003cbr\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10739407\/\" rel=\"noopener\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/10739407\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eMyasoedov N.F. et al. ACTH-derived peptides and central nervous system regulation. Journal of Peptide Science, 2011.\u003cbr\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21491577\/\" rel=\"noopener\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/21491577\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e Semax, ACTH(4–7), Synthetic Neuropeptide, CNS Signalling, Neurotrophic Peptide\u003c\/p\u003e","brand":"Zenovus Sciences","offers":[{"title":"Default Title","offer_id":54752965132629,"sku":null,"price":19.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1074\/1661\/7301\/files\/SEMAX5mg.png?v=1787734668","url":"https:\/\/zenovussciences.com\/products\/semax-5mg","provider":"Zenovus Sciences","version":"1.0","type":"link"}