{"product_id":"thymosin-beta-4-20mg-tb500","title":"Thymosin Beta 4 10mg TB500","description":"\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBatch HPLC tested at 98.5%+ purity\u003c\/li\u003e\n\u003cli\u003eStore frozen long term or in fridge when ready to be used\u003c\/li\u003e\n\u003cli\u003eSold for research purposes only\u003c\/li\u003e\n\u003cli\u003eContact us for Wholesale Orders\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003e \u003cspan\u003e \u003ca href=\"https:\/\/zenovussciences.com\/certificate-of-analysis-finder\" rel=\"noopener\" target=\"_blank\"\u003e \u003cb\u003eSearch our database for full COA analytics here.\u003c\/b\u003e \u003c\/a\u003e \u003c\/span\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eTB-500\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSynonyms \/ Designations: \u003c\/strong\u003eTB-500, Thymosin Beta-4 Fragment, Synthetic Thymosin b4–Derived Peptide\u003cbr\u003e\u003cstrong\u003eCAS Number: \u003c\/strong\u003e77591-33-4\u003cbr\u003e\u003cstrong\u003eMolecular Formula: \u003c\/strong\u003eC212H350N56O78S\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~4963.0 g\/mol\u003cbr\u003e\u003cstrong\u003ePeptide Length:\u003c\/strong\u003e 43 amino acids\u003cbr\u003e\u003cstrong\u003ePeptide Type:\u003c\/strong\u003e Synthetic peptide derived from thymosin beta-4\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e 99 % (HPLC, typical)\u003cbr\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e White to off-white lyophilised powder\u003cbr\u003e\u003cstrong\u003ePack Size:\u003c\/strong\u003e 10 mg (typical)\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Desiccated, protected from light, stored at –20 °C or below\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in water and buffered aqueous solutions\u003c\/p\u003e\n\u003ch3\u003eDescription \u0026amp; Mechanism\u003c\/h3\u003e\n\u003cp\u003eTB-500 is a synthetic peptide derived from the active region of thymosin beta-4, developed for experimental investigation of actin-binding dynamics, cell migration, and cytoskeletal organisation in controlled research settings.\u003c\/p\u003e\n\u003cp\u003eIn biochemical and cellular research models, thymosin beta-4–related peptides are studied for their interaction with G-actin, influencing actin polymerisation and cytoskeletal remodelling. Observed responses depend on peptide concentration, exposure duration, cell type, and experimental conditions.\u003c\/p\u003e\n\u003ch3\u003eApplications in Research\u003c\/h3\u003e\n\u003cp\u003e• Investigation of actin dynamics and cytoskeletal regulation\u003cbr\u003e• In vitro studies of cell migration and cellular organisation\u003cbr\u003e• Experimental models examining tissue structure and repair signalling\u003cbr\u003e• Reference peptide in thymosin beta-4–related research\u003c\/p\u003e\n\u003ch3\u003eHandling, Reconstitution \u0026amp; Stability\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eWeigh under dry conditions; peptide may be hygroscopic.\u003c\/li\u003e\n\u003cli\u003eReconstitute in sterile water or appropriate buffered aqueous solution.\u003c\/li\u003e\n\u003cli\u003eAvoid vigorous agitation during dissolution.\u003c\/li\u003e\n\u003cli\u003eFilter sterilize if required.\u003c\/li\u003e\n\u003cli\u003eAliquot and store reconstituted solutions at –20 °C or lower.\u003c\/li\u003e\n\u003cli\u003eAvoid repeated freeze–thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003ePrecautions \u0026amp; Notes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eExperimental outcomes depend on cell type and assay conditions.\u003c\/li\u003e\n\u003cli\u003eBuffer composition, pH, and ionic strength may influence peptide stability.\u003c\/li\u003e\n\u003cli\u003eAppropriate controls are recommended.\u003c\/li\u003e\n\u003cli\u003eIntended strictly for laboratory research use only.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eGupta S., Paliczak A., Delgado D. Evidence-based indications of thymosin beta-4 for wound healing and tissue regeneration. Annals of the New York Academy of Sciences, 2021.\u003cbr\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8228050\/\" rel=\"noopener\"\u003ehttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8228050\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSosne G., Qiu P., Goldstein A.L., Wheater M. Biological activities of thymosin beta-4 defined by active sites in short peptide sequences. FASEB Journal, 2010.\u003cbr\u003e\u003ca href=\"https:\/\/iovs.arvojournals.org\/article.aspx?articleid=2423767\" rel=\"noopener\"\u003ehttps:\/\/iovs.arvojournals.org\/article.aspx?articleid=2423767\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eMalinda K.M., Sidhu G.S., Mani H. et al. Thymosin beta-4 accelerates wound healing. Journal of Investigative Dermatology, 1999.\u003cbr\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10469335\/\" rel=\"noopener\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/10469335\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e TB-500, Thymosin Beta-4, Synthetic Peptide, Actin Regulation, Cytoskeletal Dynamics, Research Peptide\u003c\/p\u003e","brand":"Zenovus Sciences","offers":[{"title":"Default Title","offer_id":54752964870485,"sku":null,"price":36.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1074\/1661\/7301\/files\/TB50010mg.webp?v=1787734661","url":"https:\/\/zenovussciences.com\/products\/thymosin-beta-4-20mg-tb500","provider":"Zenovus Sciences","version":"1.0","type":"link"}