MOTS-c Peptide Stability: How Long Does It Really Last After Reconstitution?
There is much speculation about how long MOTS-c peptide remains stable after reconstitution. Some claim it degrades within hours, making it ineffective the next day. However, recent scientific studies suggest otherwise, including data from the 2022 ARVO Annual Meeting. This article explains the science and provides clear storage guidelines to help researchers and investigators get the most out of their MOTS-c peptides.
Understanding MOTS-c Stability
MOTS-c is a mitochondrial-derived peptide that is studied in metabolic and cellular research contexts. Like all peptides, its stability depends on storage conditions, solvent used for reconstitution, and exposure to environmental factors such as heat and light.
Scientific Findings on MOTS-c Stability
A study presented at the 2022 ARVO Annual Meeting investigated the stability of MOTS-c using High-Resolution Mass Spectrometry (HRMS). The key findings include:
- MOTS-c solutions were stored at 4°C and 37°C for 30 days.
- Mass spectrometry analysis showed no significant degradation over the 30-day period.
- Oxidation of methionine remained constant, indicating high peptide stability.