Tesamorelin – 20mg

• Zenovus Sciences research-grade Tesamorelin
• Batch HPLC tested for purity
• Store frozen for long-term storage or according to validated laboratory storage conditions
• Sold for research purposes only
• Contact Zenovus Sciences for wholesale orders

Tesamorelin 20mg

Synonyms / Designations: Tesamorelin, TH9507, Growth Hormone–Releasing Hormone (GHRH) analogue
CAS Number: 901758-09-6
Molecular Formula: C223H370N72O69S
Molecular Weight: ~5135.91 g/mol
Peptide Length: 44 amino acids
Peptide Type: Synthetic GHRH analogue
Purity: ≥99% (HPLC, typical)
Appearance: White to off-white lyophilized powder
Pack Size: 20mg
Storage: Desiccated, protected from light, stored at −20 °C or below
Solubility: Soluble in water and buffered aqueous solutions

Description & Mechanism

Tesamorelin is a synthetic peptide analogue of human growth hormone–releasing hormone (GHRH 1–44) designed for experimental investigation of hypothalamic–pituitary signalling and growth hormone regulation. Structural modifications are intended to provide greater stability relative to native GHRH, making Tesamorelin a useful compound for controlled laboratory research.

In biochemical and cellular research systems, Tesamorelin interacts with the GHRH receptor expressed on pituitary-derived cells and can activate intracellular signalling pathways associated with growth hormone synthesis and secretion. Experimental research may examine receptor binding characteristics, cAMP-mediated signalling, and downstream cellular responses under defined laboratory conditions. Observed effects can vary according to concentration, exposure duration, receptor expression, and experimental model.

Applications in Research

• Use as a molecular research compound for studying GHRH receptor activation and associated signalling pathways.
• Investigation of growth hormone regulatory mechanisms in pituitary cell models.
• In vitro research examining peptide stability and receptor-related activity.
• Use as a reference compound in neuroendocrine and peptide signalling research.

Specifications Summary

Purity: ≥99% (HPLC, typical)
Appearance: White to off-white lyophilized powder
Molecular Weight: ~5135.91 g/mol
Peptide Type: Synthetic GHRH analogue
Solubility: Water, buffered aqueous solutions
Storage: −20 °C, desiccated, protected from light
Pack Size: 20mg

Handling, Reconstitution & Stability

• Handle under appropriate dry laboratory conditions as the peptide may be sensitive to moisture.
• Reconstitute using an appropriate laboratory-grade aqueous solution according to the validated research protocol.
• Avoid vigorous agitation during dissolution.
• Filter sterilize when required by the applicable laboratory protocol.
• Aliquot prepared solutions when appropriate and store according to validated laboratory conditions.
• Avoid repeated freeze–thaw cycles to help maintain peptide integrity.

Precautions & Notes

• Experimental behaviour of Tesamorelin may be influenced by receptor expression, peptide concentration, exposure duration, and the selected research model.
• Buffer composition, pH, temperature, and ionic strength may affect peptide stability.
• Appropriate experimental controls are recommended to distinguish receptor-specific activity from non-specific effects.
• Intended strictly for laboratory research use and not for human or veterinary application.

References

Thorner M.O. et al. Growth hormone–releasing hormone and its analogues. Endocrine Reviews, 1997.

Bowers C.Y. Growth hormone–releasing peptides and neuroendocrine regulation. Endocrine Reviews, 2001.

Vance M.L. Growth hormone releasing hormone and pituitary signalling. Journal of Clinical Endocrinology & Metabolism, 2003.

Keywords: Tesamorelin, TH9507, GHRH Analogue, Growth Hormone Regulation, Synthetic Peptide, Tesamorelin 20mg